AHK-Cu

AHK-Cu is a tripeptide-metal complex composed of the amino acid sequence alanine-histidine-lysine bound to a divalent copper ion. The copper chelation is primarily facilitated through the histidine residue's imidazole ring and the terminal amine groups. This compound has been investigated in research settings for its potential effects on fibroblast proliferation, collagen and elastin production, glycosaminoglycan synthesis, and angiogenic signaling pathways.

In experimental models, AHK-Cu has demonstrated the ability to modulate gene expression related to tissue remodeling, influence metalloproteinase activity, and promote antioxidant enzyme expression. The copper ion serves as a critical cofactor in various enzymatic processes involved in wound healing and extracellular matrix formation. Research has explored its effects on keratinocyte migration, dermal thickness, and inflammatory mediator regulation.

Studies suggest AHK-Cu may influence the TGF-β signaling pathway and stimulate production of various growth factors in controlled laboratory conditions. The peptide's copper-binding properties also contribute to its potential antioxidant characteristics through regulation of superoxide dismutase activity.

This product is intended strictly for laboratory research purposes only. Not for human consumption, clinical use, or any form of in vivo application. Researchers should follow appropriate safety protocols when handling this compound.