Name: Vesugen
Brand: Biotech Compounds
Price: 75.99 USD
Availability: Discontinued
Rating: 4.8 (127 reviews)

Question 1

What is Vesugen and what has research studied it for?

Accepted Answer

Vesugen is a synthetic tripeptide bioregulator made of lysine, glutamic acid, and aspartic acid, written Lys-Glu-Asp or KED. It belongs to the Khavinson family of short peptide bioregulators, a group of two to four amino acid peptides each associated with a particular tissue. Vesugen is the member linked to the vascular system. Research studies have examined Vesugen in models of endothelial cell function, blood vessel wall integrity, and cellular aging.

Question 2

How does Vesugen work according to published research?

Accepted Answer

The Khavinson bioregulator hypothesis, explored in published research, proposes that short peptides such as Vesugen pass into the nucleus and interact with DNA to modulate the expression of tissue specific genes. In cell culture studies, researchers have reported that Vesugen influenced the expression of connexins, the proteins that form gap junctions between endothelial cells. Vesugen has been observed in these models to affect markers of endothelial cell proliferation and intercellular communication.

Question 3

What is the primary research area for Vesugen?

Accepted Answer

The primary research area for Vesugen is vascular biology, with a focus on the endothelial cells that line blood vessel walls. In cell culture studies, researchers have reported that Vesugen supported the growth and organization of endothelial cell layers. Animal model research has examined Vesugen for its effect on measures of vascular wall integrity. These studies use Vesugen as a compact model compound for peptide mediated regulation of vascular tissue.

Question 4

What secondary research has examined Vesugen?

Accepted Answer

A secondary research area for Vesugen is cellular aging. Researchers have studied Vesugen in aging cell cultures and in older animal models to see whether it alters gene expression patterns associated with senescence in vascular tissue. Published research from bioregulator groups has also compared Vesugen with other Khavinson peptides to map which amino acid combinations correspond to which tissues. Limited clinical reports have appeared in the same literature.

Question 5

What type of evidence exists for Vesugen research findings?

Accepted Answer

Evidence for Vesugen comes mainly from in vitro cell culture work and animal models, much of it published by Russian bioregulator research groups. A smaller number of clinical observations have been reported in that literature. Vesugen is not an approved drug in the United States and has not gone through FDA regulated clinical trials. Biotech Compounds supplies Vesugen as a research grade lyophilized tripeptide for laboratory investigation of these mechanisms.

Question 6

What is the difference between Vesugen and Epitalon?

Accepted Answer

Vesugen and Epitalon are both Khavinson peptide bioregulators but are associated with different tissues. Vesugen is the tripeptide Lys-Glu-Asp, and research studies have examined it in vascular endothelium models. Epitalon is the tetrapeptide Ala-Glu-Asp-Gly, and researchers have studied it in pineal gland and telomerase related aging models. Both are studied under the same gene regulation hypothesis, so Vesugen and Epitalon are often compared in bioregulator research.

Question 7

What is the difference between Vesugen and Thymogen?

Accepted Answer

Vesugen and Thymogen are both short Khavinson bioregulators that differ by target tissue. Vesugen is the tripeptide Lys-Glu-Asp studied in vascular and endothelial models. Thymogen is the dipeptide Glu-Trp, and research studies have examined it in immune and thymic models. The two share a glutamic acid residue but are otherwise distinct, and researchers comparing tissue selectivity of short peptides often run Vesugen and Thymogen side by side.

Question 8

How is Vesugen reconstituted for laboratory research?

Accepted Answer

Vesugen is supplied as a lyophilized powder. To reconstitute, Bacteriostatic Water or sterile water is added slowly down the inner wall of the vial so it runs onto the Vesugen powder. The vial is then gently swirled until the solution is clear. Because Vesugen is a small, highly polar tripeptide it dissolves easily in water, but the vial should not be shaken as a matter of good peptide handling practice.

Question 9

How should Vesugen be stored before and after reconstitution?

Accepted Answer

Lyophilized Vesugen should be stored cold, ideally at minus 20 C, in a sealed vial protected from light and moisture. After reconstitution, Vesugen solution should be refrigerated at 2 to 8 C, protected from light, and used within a short period. Repeated freeze thaw cycles should be avoided. Short peptides such as Vesugen are generally more stable in solution than long chain peptides, but cold storage still preserves the quality of the material.

Question 10

Is Vesugen from Biotech Compounds third-party tested for purity?

Accepted Answer

Yes. Vesugen from Biotech Compounds is listed at 99 percent or higher purity and each lot is tested by an independent laboratory. The Certificate of Analysis for Vesugen is available on the product page and reports identity and purity for that batch. Researchers should confirm the lot number on the Vesugen vial matches the posted COA before starting an experiment.

Question 11

What is the molecular weight and formula of Vesugen?

Accepted Answer

Vesugen has a molecular weight of approximately 390.39 g/mol and the molecular formula C15H26N4O8. It is a tripeptide made of three amino acids: lysine, glutamic acid, and aspartic acid. The combination of one basic residue and two acidic residues gives Vesugen a distinctive charge profile, which the bioregulator research literature points to when discussing its proposed interaction with DNA.

Question 12

Is Vesugen approved for human use in the United States?

Accepted Answer

No. Vesugen from Biotech Compounds is sold strictly as a research material for laboratory research by qualified researchers and research organizations. Purchasers must be 21 years of age or older. Vesugen sold here is not a drug or a dietary supplement, has not been approved by the FDA, and is not for human or animal consumption. It is intended only for laboratory investigation.

VesugenVesugen is a synthetic tripeptide bioregulator (Lys-Glu-Asp) studied for its role in supporting vascular endothelial function and blood vessel integrity.

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