Lipo-C with B Vitamins

Lipo-C is a multi-component aqueous research formulation supplying eight amino acids, water-soluble vitamins, and enzymatic cofactors at defined concentrations in a single matrix. It is prepared for laboratory use as a reference material in analytical method development, compound stability and solubility characterization, and cofactor-dependent in vitro enzyme assays. The components are those grouped in biochemical literature under the lipotropic classification, combined with three water-soluble B vitamins.

Active Ingredients (per mL)

L-Carnitine (100mg/mL) — A zwitterionic quaternary ammonium compound. Characterized in biochemical reference literature as the acyl-group carrier of the carnitine palmitoyltransferase system. Commonly used as a reference standard in acylcarnitine profiling and mass spectrometry method development.

Arginine (20mg/mL) — A basic proteinogenic amino acid and the characterized substrate of nitric oxide synthase. Used in enzymology reference work on the urea cycle, and as a solubility and ionic strength modifier in mixed aqueous preparations.

Methionine (25mg/mL) — A sulfur-containing essential amino acid and the precursor to S-adenosylmethionine, the principal methyl group donor in one-carbon transfer chemistry. A reference compound in transmethylation and transsulfuration pathway analysis.

Inositol (50mg/mL) — Supplied as the myo- isomer, a carbocyclic polyol forming the headgroup of the phosphoinositide class of membrane phospholipids. Used as a reference standard in polyol chromatographic separation and in phosphoinositide chemistry.

Choline (50mg/mL) — A quaternary amine and the headgroup of phosphatidylcholine, one of the principal structural phospholipids of the cell membrane. Referenced in phospholipid biosynthesis chemistry, including the Kennedy pathway, and in one-carbon transfer studies.

Vitamin B5, Dexpanthenol (25mg/mL) — The alcohol analog of pantothenic acid, converting to pantothenate in aqueous solution. Pantothenate forms the structural core of coenzyme A, the acyl group carrier in a wide range of characterized enzymatic acyl transfer reactions.

Vitamin B6, Pyridoxine (25mg/mL) — Precursor to pyridoxal-5-phosphate, the cofactor for more than one hundred characterized enzymes, including the aminotransferase and decarboxylase families. A standard cofactor addition in in vitro enzyme assay preparation.

Vitamin B12, Cyanocobalamin (1mg/mL) — A cobalt-centered corrinoid, and the cobalamin form most resistant to photodegradation, which is why it is generally selected for formulation work. The characterized cofactor of methionine synthase and methylmalonyl-CoA mutase, and a common reference standard in cobalamin assay work.

The eight components span several distinct molecular classes — zwitterionic amino acids, quaternary amines, cyclic polyols, corrinoids, and pyridine derivatives — which makes the formulation a useful single matrix for multi-class compatibility testing, forced degradation profiling, pH-dependent solubility characterization, and chromatographic separation method development.

Disclaimer: Lipo-C is supplied strictly for research and laboratory use only. This product is not a drug, dietary supplement, or medical device. It is not intended for human or animal consumption, and not for therapeutic, diagnostic, or clinical application. It has not been evaluated by the FDA, and no statement here should be read as a claim to diagnose, treat, cure, or prevent any condition. All handling should be performed by qualified researchers in accordance with applicable laboratory safety protocols and institutional guidelines.