Name: Pinealon
Brand: Biotech Compounds
Price: 42.99 USD
Availability: InStock
Rating: 4.8 (127 reviews)

Question 1

What is Pinealon and what has research studied it for?

Accepted Answer

Pinealon is a synthetic tripeptide made of glutamic acid, aspartic acid, and arginine, written Glu-Asp-Arg or EDR. It belongs to the family of short regulatory peptides known as Khavinson peptides, which were developed as tissue-specific bioregulators. Research studies have examined Pinealon mainly in models of brain aging, oxidative stress, and neuronal cell survival. It is supplied as a lyophilized powder for laboratory research.

Question 2

How is Pinealon reported to work in research studies?

Accepted Answer

Researchers have proposed that Pinealon, like other short Khavinson peptides, is small enough to enter cells and interact directly with DNA and chromatin. In vitro studies have reported that Pinealon can change the expression of genes linked to cell survival and neuronal differentiation. Published research also suggests the peptide reduces reactive oxygen species in stressed cells, which is the mechanism most often cited in Pinealon studies.

Question 3

What has research examined about Pinealon and brain cells?

Accepted Answer

The primary research area for Pinealon is neuroprotection. In cell culture studies, researchers reported that Pinealon reduced markers of oxidative damage and cell death in neurons exposed to stress. In rodent models of prenatal hypoxia, studies have observed better performance on learning and memory tasks in animals given Pinealon compared with untreated animals. These findings are the reason Pinealon appears in neuroscience and aging research.

Question 4

Has Pinealon been studied in aging and gene expression research?

Accepted Answer

Yes. A secondary line of Pinealon research looks at cellular aging. In vitro studies have examined how Pinealon affects the expression of genes involved in proliferation, apoptosis, and differentiation in aging cell cultures, including neuronal and pineal tissue lines. Researchers working in the Khavinson bioregulator tradition have reported that Pinealon and related short peptides appear to restore some age-associated changes in these culture systems.

Question 5

What type of evidence supports Pinealon research?

Accepted Answer

The evidence for Pinealon comes mostly from in vitro cell culture work and rodent studies, much of it published by Russian research groups. There are also small human observational reports in the bioregulator literature, but Pinealon has not gone through large controlled clinical trials and is not an approved drug in the United States. Pinealon should be considered an investigational research compound with a limited but growing body of preclinical data.

Question 6

What is the difference between Pinealon and Epitalon?

Accepted Answer

Pinealon and Epitalon are both short synthetic Khavinson peptides sold by Biotech Compounds, but they differ in sequence and research focus. Pinealon is the tripeptide Glu-Asp-Arg and is studied mainly for neuroprotection and brain aging. Epitalon is the tetrapeptide Ala-Glu-Asp-Gly and is studied mainly for telomerase activity and pineal gland function in aging models. Researchers choose between them based on which tissue system a study is examining.

Question 7

How is Pinealon reconstituted for research?

Accepted Answer

Pinealon is supplied as a lyophilized powder that is freely soluble in water because of its highly polar, charged amino acids. For laboratory preparation, Bacteriostatic Water is added slowly down the inside wall of the vial. The vial is then swirled gently until the powder dissolves. Pinealon should never be shaken, since agitation can degrade peptides. Sterile technique and a clean work surface are recommended for every reconstitution.

Question 8

How should Pinealon be stored before and after reconstitution?

Accepted Answer

Lyophilized Pinealon should be stored at minus 20 C, protected from light and moisture, and kept sealed until use. Once reconstituted, Pinealon should be refrigerated at 2 to 8 C and used within a limited window. Repeated freeze and thaw cycles should be avoided because they can break down the peptide. Keeping the vial away from light and heat helps preserve the stability of Pinealon in the laboratory.

Question 9

Is Pinealon third-party tested and does it come with a COA?

Accepted Answer

Yes. Pinealon from Biotech Compounds is listed at 99 percent or higher purity and is third-party tested to verify identity and purity. A Certificate of Analysis is available on the Pinealon product page so researchers can review the testing results for each lot before it is used in a study. This documentation supports reproducible laboratory work and lets research organizations keep records for their own quality systems.

Question 10

What is the molecular weight and formula of Pinealon?

Accepted Answer

Pinealon has the molecular formula C15H24N6O8 and a molecular weight of approximately 416.39 g/mol. It is one of the smallest peptides in the Biotech Compounds catalog, with only three amino acids. The low molecular weight and the presence of two acidic residues and one basic residue give Pinealon distinct electrostatic properties, which researchers cite when explaining how the peptide may interact with DNA and cell membranes.

Question 11

Is Pinealon approved for human use?

Accepted Answer

No. Pinealon is not an approved drug and is not a dietary supplement. Biotech Compounds sells Pinealon strictly as a research material for laboratory research by qualified researchers and research organizations. Purchasers must be 21 years of age or older. Pinealon is not intended for human or animal consumption and is not intended to diagnose, treat, cure, or prevent any disease.

PinealonPinealon is a synthetic tripeptide with the sequence Glu-Asp-Arg (EDR), available as a lyophilized powder for laboratory research.

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